Ensure applications comply with accessibility standards such as WCAG (Web Content Accessibility Guidelines), Section 508, or ADA (Americans with Disabilities Act Use tools like JAWS, NVDA, VoiceOver, and screen readers to test accessibility features. Perform manual testing for keyboard navigation, focus management, and assistive technology compatibility. Create test cases specifically targeting accessibility features, including color contrast, font size, and alternative text for images. Identify accessibility issues and log defects with detailed descriptions and recommendations for resolution. Document test results and provide accessibility compliance reports. Highlight areas of improvement and track progress over time.