Job Title: Next-Generation Sequencing (NGS) Lead
Location: Domlur, Bangalore
Job Summary:
We are seeking a highly skilled and experienced professional to lead our Next-Generation Sequencing (NGS) operations. The ideal candidate will have over 10 years of experience in life sciences and genomics, with extensive hands-on expertise in NGS library preparation, sequencing, and troubleshooting. This role involves managing a team, optimizing workflows, and delivering high-quality sequencing solutions using Illumina and Oxford Nanopore platforms.
Key Responsibilities:
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Lead and manage the NGS laboratory team, ensuring timely and accurate project delivery.
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Plan and execute library preparation and sequencing workflows for Illumina Sequencers.
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Optimize protocols for various sequencing applications, including metagenomic sequencing, whole-genome sequencing, RNA-seq, exome-seq, and small RNA-seq.
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Perform troubleshooting and resolve issues during library preparation, sequencing, and data analysis.
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Conduct nucleic acid extraction and quantification from diverse sample types using advanced techniques.
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Ensure quality control through Qubit, Agilent TapeStation, and other analytical methods.
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Develop and standardize workflows and maintain detailed documentation, including SOPs and experimental plans, for ISO compliance and audits.
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Provide technical guidance to internal and external stakeholders on NGS experimental design and data interpretation.
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Deliver technical training, webinars, and presentations to customers and team members.
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Collaborate with product support teams to address reagent and sequencing system issues.
Required Skills and Qualifications:
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Extensive experience with NGS platforms and techniques, including Illumina (MiSeq, NextSeq, NovaSeq etc)
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Proficiency in library preparation techniques such as Nextera, TruSeq, and NEB workflows.
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Strong molecular biology skills, including PCR, qPCR, and DNA/RNA quantification.
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Familiarity with microarray techniques, including gene expression and array CGH assays.
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Proven ability to troubleshoot and optimize complex laboratory workflows.
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Experience in team management and leadership roles.
Preferred Qualifications:
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MTech/Ph.D in Genetics, Biotech, Molecular Biology or related fields
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Publications in peer-reviewed journals highlighting expertise in genomics or molecular biology.
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Experience in customer-facing roles or technical support in the genomics field.
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Experience in Bioinformatics for data QC, data analysis specifically for metagenomics.
Why Join Us?
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Work in a cutting-edge genomics environment with advanced technologies.
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Collaborate with a dynamic team of scientists and technical experts.
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Contribute to impactful projects in genomics and life sciences.
