Responsibilities MIS Managers have a variety of challenging and important responsibilities. The specific duties of an MIS Manager typically revolves around the management of a company’s acquisition, storage, retrieval and analysis of data. Collecting, analyzing and disseminating data in a time-sensitive manner to the management Preparing and presenting reports based on the analysis of this data Assisting in strategic planning and implementation of new or existing information systems Maintaining and updating databases to ensure information accuracy Ensuring the security of the company’s digital documents and sensitive information, should have extensive experience in networking hardware and software, a keen eye for detail, and be able to monitor the entire system and report any potential issues.