The Global HEOR Economic Modeling Senior Associate plays a critical role in supporting Amgen’s global market access and health economics strategy through the development of health economic models. This role will partner closely with team lead and Global HEOR Product Leads to ensure strong alignment with product strategy. The Economic Modeling Senior Associate will develop cost-effectiveness, budget impact, and other health economic models that reflect clinical and real-world data to inform HTA and payer decision-making.
Design and develop hands on global core health economic models for products at all stages of development and launch, using cost-effectiveness/cost-utility (e.g., markov, partitioned survival model), cost minimization, budget impact, and other techniques, as appropriate.
Program models in software such as Excel, R, or Python, ensuring accurate integration of clinical, real-world data, epidemiological, and economic inputs.
Conduct statistical analyses of clinical trial and real-world data to generate inputs including treatment effects, survival extrapolations, resource use, and health utility estimates.
Design and conduct advanced evidence synthesis, including network meta-analyses (NMA) and matching-adjusted indirect comparisons (MAIC), to inform comparative effectiveness.
Implement various types of scenario and sensitivity analyses such as univariate, multivariate, and probabilistic analyses to test model robustness.
Deliverables will include the model structure, programmed model, technical report, user's guide, and presentation files and publications.
Work closely with team lead and HEOR Product Leads to ensure economic models follow product strategy.
Monitor and integrate evolving HTA guidelines, payer requirements, and methodological advancements.
Interpret complex economic findings to technical and non-technical audiences.
